Bromfenac Impurity 6 CAS 241496-82-2(free acid)
| CAS No. | 241496-82-2(free acid) |
| Molecular Formula | C14H9BrNO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Bromfenac Impurity 6 (CAS 241496-82-2(free acid)) is a certified pharmaceutical impurity reference standard with the molecular formula C14H9BrNO3Na and a molecular weight of 342.12 g/mol.
Owing to a salt form, a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution, Bromfenac Impurity 6 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 342.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Bromfenac Impurity 6 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H9BrNO3 Na |
| Molecular Weight | 342.12 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromfenac Standards
- Bromfenac Impurity 30 (CAS 102414-22-2)
- Bromfenac Sodium Sesquihydrate (CAS 120638-55-3)
- Bromfenac Impurity 30 (CAS 1279501-08-4)
- Bromfenac Impurity 3 (CAS 1391052-54-2)
- Bromfenac Impurity 76 (CAS 1623751-93-8)
- Bromfenac Impurity 33 (CAS 1644279-16-2)
- Bromfenac Impurity N2 (CAS 1798431-98-7)
- Bromfenac N-β-D-Glucoside (CAS 212266-82-5)
Recommended Standards
- Tafluprost Impurity 11 (CAS CATO-C4X-216311)
- Delamanid Impurity N1 (CAS 287952-66-3)
- Fulvestrant EP Impurity B (CAS 98008-06-1)
- 2,6-Bis(bromomethyl)pyridine Hydrobromide (CAS 73004-40-7)
- 1-desoxymethylsphinganine-d5 (CAS 1246298-43-0)
- ETHYL 2-(6-CYANO-1H-INDOL-1-YL)ACETATE (CAS 796856-93-4)
- 4-Chloro-6-(difluoromethyl)-5-fluoronicotinoyl chloride (CAS 1806927-63-8)
- 4-Iodo-2-methyl-6-nitroaniline (CAS 532934-93-3)
- 2-(1,4-Dibenzylpiperazin-2-yl)acetonitrile (CAS 70403-11-1)
- Endo-Gly4-Semaglutide (CAS CATO-C4X-222679)
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